Research Associate/Sr. Research Associate, Structural Biology & Protein Sciences | ClinLab Staffing

Our client located in Cambridge, MA is seeking a Research Associate with extensive experience in molecular cloning, protein expression, protein purification and protein characterization. This person will have experience working with CRISPR proteins. The individual will assist with the production of a variety of proteins for assay development and structural characterization.

Primary Responsibilities:

  • Work closely with a team of scientists across the Discovery platform to clone and express target proteins in a variety of systems (e.g. bacterial, mammalian or yeast, as appropriate) and establish protocols for their successful purification
  • Design, plan and perform biochemical and functional characterization of the target proteins with guidance from team members
  • Contribute to the scientific strategy and output of the Protein Sciences team


  • BS or MS with ideally 2 or more years of experience in molecular biology, biochemistry, protein sciences with relevant industrial laboratory experience
  • Experience in molecular cloning, protein expression, and protein purification is a must
  • Candidate must be comfortable with routine use of FPLC (affinity, size exclusion, ion exchange chromatography), SDS-PAGE, and UV-VIS spectroscopy
  • Experience in mammalian cells is desirable
  • Familiarity with a variety of assays looking at DNA and RNA interactions will be a plus
  • Experience in crystallography or cryo-EM sample preparation will be a plus
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