Research Associate – Translational Biology

Our Translational Biology department is seeking an experienced Research Associate to conduct oncology target validation and mechanism of action studies in a highly collaborative, goal-oriented team environment. The position requires excellent hands-on experience with commonly used techniques in cancer cell biology and/or chromatin biology.

Requirements:

• B.S./M.S. degree in life sciences with at least 1-3 years of relevant research experience in an academic or industrial setting.
• Excellent cell culture experience with cancer cell lines, setting up multi-well assays and using fluorescence and luminescence based read-out as a functional endpoint.
• In depth knowledge of cell and molecular biology techniques, including cell transfection (cDNA, siRNA, shRNA and/or CRISPRs), stable cell clone generation, RNA/DNA extraction, qPCR, SDS-PAGE and Western blotting.
• Flexibility and willingness to work across diverse areas, ability to develop and evaluate novel assays for a wide variety of biological/phenotypic endpoints and to support general research activities within the group.
• Detail oriented with the ability to work in a fast paced environment under tight deadlines.
• Strong communication and organization skills, keeping good scientific records, and giving updates at team meetings.

Responsibilities:

• You will be expected to work closely with scientists to design and execute cell-based phenotypic and mechanism of action assays in a variety of assay platforms.
• Perform standard cell and molecular biology techniques according to established protocols.
• Generate, analyze, and catalog data using database tools as well as data analysis, plotting and graphing software.
• Document all work in electronic notebooks and present data internally at group meetings