SUMMARY:

Our client is seeking an experienced, highly motivated Scientist to advance downstream process development for their genetic medicines.

RESPONSIBILITIES:

  • Develop a technical plan for laboratory studies to enable a scalable downstream process for the purification
  • Perform in-house experiments and supervise efforts related to the development of downstream process steps including cell harvest, lysis, depth filtration, chromatography steps (IEX, affinity, mixed mode, etc.), viral filtration, and UFDF.
  • Orchestrate runs of the established process and enable scale-up manufacturing process at contract manufacturing organization (CMO)
  • Collaborate with contract research organizations to assist external development efforts
  • Assist in the generation and review of protocols, reports, and batch records
  • Prepare, analyze, and present data internally to cross functional teams

Requirements:

  • MS or PhD in Biochemistry, Bioengineering, Biotechnology or related discipline
  • Minimum 10 years with MS or 5 years with PhD of relevant industry experience
  • Experience in working with an oligonucleotide-based purification process
  • Experience in PD and manufacturing activities in a GMP environment
  • Results-driven with excellent attention to details
  • Ability to manage multiple projects and responsibilities simultaneously
  • Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines
  • Ability to work with others to troubleshoot complex technical and scientific problems while showing independence in execution and thought processes.
  • Previous experience managing in-house and CRO work preferred
  • Articulate and confident communication and interpersonal skills
  • Ability to diversify technical skill sets in a fast-paced organization
Submit Resume

To apply for this job email your details to info@clinlabstaffing.com